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Dow AgroSciences Partners With Chromatin for Research and Technology Advances

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The combination of Mini-Chromosome Platform and EXZACT Precision Technology will bring products to the market more quickly.

| November 16, 2009

INDIANAPOLIS and CHICAGO –  Dow AgroSciences, a wholly owned subsidiary of The Dow Chemical Company, and Chromatin Inc. announced that the companies have entered into two agreements:  the first provides Dow with rights to Chromatin’s Mini-Chromosome technology and the second establishes an exclusive research and license agreement to combine EXZACT Precision Technology with Mini-Chromosomes, creating a novel technology platform for the development of next generation traits in corn, soybeans and canola. 

“One of the most critical challenges facing the plant biotechnology industry is the production of cost-competitive multi-gene and stacked trait products,” said Dan Kittle, vice president R&D for Dow AgroSciences. “Today, there are two technical solutions to multi-gene stacking, pathway engineering and simplified plant breeding in plants. Those technical solutions are site-specific genome modification and building of customized chromosomes.”

Dow AgroSciences’ EXZACT Precision Technology provides a versatile and comprehensive toolkit for targeted genome modification on plants. Its demonstrated ability to specifically and efficiently target plant genome sequences delivers a means for engineering multi-gene stacks, editing native genes and deleting undesirable traits. 

Chromatin’s Mini-Chromosomes are autonomous genetic elements built to deliver multiple traits of importance to growers, processors, and consumers and to accelerate the development and launch of new products.

Combining Mini-Chromosomes and EXZACT Precision Technology will create a technology synergy that delivers flexibility and efficiencies for modifying trait combinations on the mini-chromosome, inside the plant, in real time.

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